Facets of the research process are often taught and discussed in isolation. I will offer an integrative perspective. I will argue that research should originate from an important question that matters to scholars and/or practitioners – that drives impact. Then, the facets of the research process including sampling, research design, measurement, and analysis need to be integrated and aligned with the research question for optimal value. These facets drive inferences concerning external, internal, construct, and statistical conclusion, respectively, as elements of a unified validity framework. I will then differentiate and illustrate different types of multi-methods and mixed-methods designs suitable for different purposes.